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secobarbital will reduce the extent or effect of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Effect of coadministering a solid CYP3A4 inducer with fedratinib hasn't been analyzed.Mimic the Authorities: Immerse oneself in English by Hearing audiobooks, podcasts, or movies with subtitles. Try sh